| 1400 - 1500 What if we continued sailing westward from Europe? Would we reach India sooner? |  |
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 | 1500 - 1600 What if the Earth revolves around the Sun? Would that explain the movements of the other planets better? |
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| 1600 - 1700 What if for the same reason the apple falls to the ground and the Earth revolves around the Sun? |  |
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 | 1700 - 1800 What if we heated water and used the steam to power machines? |
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| 1800 - 1850 What if we harnessed the same power that creates lightning to build an electric battery? |  |
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 | 1850 - 1875 What if we built a space cannon and let it fly from the Earth to the Moon? |
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| 1875 - 1900 What if we created rays of light that could shine through the human body revealing its interior? |  |
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 | 1900 - 1910 What if time passes more slowly for passengers traveling in a fast-moving spaceship? |
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| 1910 - 1920 What if continents move around the surface of the Earth? Could it be the reason for earthquakes? |  |
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 | 1920 - 1930 What if God plays dice and the building blocks of nature behave in an uncertain way? |
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| 1930 - 1940 What if heavy hydrogen nuclei could be forced to react with each other and fused into helium? |  |
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 | 1940 - 1950 What if we used binary arithmetic to create machines that carry out mathematical calculations? |
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| 1950 - 1960 What if a computer program became intelligent enough to pass a test in which it cannot be distinguished from a human being? What if a program were able to beat the best chess player in the world? |  |
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 | 1960 - 1970 What if the universe once began as an infinitesimal point and has been expanding ever since? |
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| 1970 - 1980 What if a commercial airplane could transport passengers from London to New York in less than 4 hours? |  |
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 | 1980 - 1985 What if every household could afford its own personal computer? |
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| 1985 - 1990 What if we discovered extrasolar planets orbiting other star systems? |  |
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 | 1990 - 1995 What if the Internet allowed people to retrieve information with a few simple mouse clicks? |
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| 1995 - 2000 What if we decoded and understood the entire human genome? Would we be able to cure almost all diseases? |  |
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 | 2000 - 2005 What if nanorobots were introduced into the human body to repair damaged tissue and destroy harmful viruses? |
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| 2005 - 2010 What if petascale computing systems were developed, capable of performing quadrillions of calculations per second? |  |
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 | 2010 - 2015 What if we found new ways and encountered new opportunities to send humans to Mars? |
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| 2015 - 2020 What if we built androids that behave almost like human beings? |  |
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 | 2020 - 2025 What if we took high resolution pictures of terrestrial planets orbiting other stars? Will some of them resemble Earth? |
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| 2025 - 2030 What if we did accomplish nuclear fusion in a power plant on Earth? |  |
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 | 2025 - 2030 What if we constructed an artificial womb that nurtures human embryos into healthy babies? |
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| 2030 - 2035 What if we developed smart materials that would last thousands of years under the harsh conditions of outer space? |  |
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 | 2035 - 2040 What if we could equip spaceships with new propulsion systems allowing for reliable long-distance space travel? |
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| 2040 - 2045 What if virtual reality technology could be used for long-distance space travel helping human space crews maintain their psychological health? |  |
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 | 2045 - 2050 What if a technological singularity came into existence, a smarter-than-human entity which would rapidly accelerate technological progress beyond the capability of human beings? |
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| 2050 - 2055 What if an extinction level event on Earth became imminent? How would we prepare for it? |  |
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 | 2055 - 2060 What if it were possible to send frozen human embryos on an interstellar space expedition? |
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| 2060 - 2065 What if we built a space elevator that drastically reduces costs of lifting off materials from Earth? |  |
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 | 2065 - 2070 What if the practice of cryopreserving humans could overcome the obstacles of tissue damage? |
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| 2070 - 2075 What if helium-3 mining became widespread in the solar system? |  |
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 | 2075 - 2080 What if there were smarter and simpler planet engineering technologies for terraforming other planets? |
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| 2080 - 2085 What if we stored the genomes of all living species in digital seed banks and find ways to bring them to life in the distant future? |  |
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 | 2085 - 2090 What if the SETI project at last recorded a message from an intelligent extraterrestrial species? |
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| 2090 - 2095 What if there were a complete merger between human technology and human intelligence, could we decorate walls using our thoughts? |  |
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 | 2095 - 2100 What if we could slow down the aging process, halt it entirely, or even reverse it? |
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